AMCHAM, in collaboration with EY, released the knowledge paper ‘The Agentic AI-First Global Capability Center’ which explores how the next generation of global capability centers are evolving into AI-first, intelligence-driven hubs that are transforming enterprise operations and creating strategic global impact. With the rise of generative AI and autonomous agents, enterprises must move beyond incremental automation and redesign core activity systems and operating models around AI. Future GCCs will embed AI as a structural execution layer, reorganize processes around orchestration rather than hierarchy, and shift human roles toward oversight and augmentation. This transformation can deliver significant economic value but depends on factors such as technology readiness, innovation culture, and investment in transformation. The paper was released by Mr. Jayesh Ranjan, IAS, Special Chief Secretary, Metropolitan Area and Urban Development Department and Youth Advancement, Tourism, Culture and Sports Department, Government of Telangana at AMCHAM’s GCC Summit 6.0 in Hyderabad.